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What is the definition of a Schedule I drug?

  1. High potential for abuse with severe risk for dependence

  2. No accepted medical use or a lack of accepted safety for use under medical supervision

  3. Lower potential for abuse with limited dependence risk

  4. Abuse potential less than those in Schedules I and II

The correct answer is: No accepted medical use or a lack of accepted safety for use under medical supervision

A Schedule I drug is defined by its lack of accepted medical use and the absence of safety for use under medical supervision. This classification indicates that such substances are considered to have a high potential for abuse and do not meet the criteria established for medical use, making them illegal to prescribe or administer. This definition is crucial for understanding drug scheduling, as it addresses the lack of any accepted therapeutic benefits and the associated dangers. Other classifications distinguish between varying degrees of potential abuse and dependency, but Schedule I is specifically characterized by its severe restrictions due to the identified health and societal risks. Understanding this classification helps clarify the legal and medical frameworks governing controlled substances.